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To determine the toxicity and efficacy of combined therapy with cisplatin and prolonged infusion topotecan as front line therapy in women with epithelial ovarian cancer.Women with previously untreated, measurable and non-measurable epithelial ovarian cancer, stages Ic–IV were eligible. Patients were treated with cisplatin 75 mg/m 2 on day 1, followed by topotecan 0.3 to 0.4 mg/m 2 ...
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