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Effective defense of Arabidopsis against filamentous pathogens requires two mechanisms, both of which involve biosynthesis of tryptophan (Trp)‐derived metabolites. Extracellular resistance involves products of PEN2‐dependent metabolism of indole glucosinolates (IGs). Restriction of further fungal growth requires PAD3‐dependent camalexin and other, as yet uncharacterized, indolics.
This study focuses...
•A hallmark of the innate immune system of plants is the biosynthesis of low‐molecular‐weight compounds referred to as secondary metabolites. Tryptophan‐derived branch pathways contribute to the capacity for chemical defense against microbes in Arabidopsis thaliana.
•Here, we investigated phylogenetic patterns of this metabolic pathway in relatives of A. thaliana following inoculation with filamentous...
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