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The measurement of malondialdehyde (MDA) in biological fluids remains a popular method for the quantification of free radical damage to lipids in vivo. Several diseases of prematurity are thought to be related to oxidative injury and previous studies have found elevated MDA in plasma and urine in preterm infants. Our aim was to investigate the relationship between plasma and urinary MDA levels in...
Frequent blood transfusions may produce changes in iron status which can give rise to oxygen-derived free-radical (ODFR) generation and oxidative injury. Preterm infants developing chronic lung disease (CLD) receive significantly more transfusions. A total of 73 very preterm infants had weekly estimations of serum iron, transferrin, transferrin saturation, ferritin, caeruloplasmin, bleomycin detectable...
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