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A cDNA designated as AZ3B has been isolated from a differentiated HL-60 cell cDNA library with a probe derived from theN -formyl peptide receptor gene. The 1.97-kb cDNA encodes a novel G protein-coupled receptor (GPCR) with 482 amino acids. In addition to the predicted 7 transmembrane domains common to all GPCRs, the protein encoded by AZ3B contains a large extracellular loop of 172 amino acids...
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