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1α,25-Dihydroxyvitamin D 3 [1,25(OH) 2 D 3 ] inhibits growth of cells derived from a variety of tumors in vitro and in vivo. Proliferation in vitro of human SCC25 cells, derived from a primary squamous cell carcinoma (SCC) of the tongue, was blocked by 1,25(OH) 2 D 3 and its analog EB1089. A similar effect was observed with 13-cis retinoic acid (RA), which has...
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