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Nanoparticles exhibiting enzymatic functions have garnered considerable attention due to their structural robustness and the profusion of active sites that can be introduced to a single nanosized particle. Here we report that nanosized mixed‐metal zeolitic imidazolate frameworks (ZIFs) show a superoxide dismutase (SOD)‐like catalytic activity. We chose a ZIF composed of copper and zinc ions and 2‐methylimidazole,...