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The effects of carbon tetrachloride (CCl 4 ) treatment on acute liver damage in knock out (heat shock proteins—HSP70−/−) mice and wild-type (C57BL/6) mice were examined. Acute liver injury was induced by a single intraperitoneal injection of 0.3ML/kg CCl 4 in olive oil. Mice were sacrificed at 12, 24, 48 and 72h after treatment. To assess hepatotoxicity, alanine transaminase, neutrophil...
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