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PurposeTo examine sex differences in fractional anisotropy of the white matter across the whole brain, controlling for head size variation.
Materials and MethodsA total of 238 normal subjects aged 40–49 years were included in this study. Diffusion tensor images were acquired at 3 Tesla using a single‐shot spin‐echo echo‐planar sequence. With use of tract‐based spatial statistics (TBSS), sex differences...
Head size markedly differs among individuals. To our knowledge, there have been no studies that systematically investigated the effect of head size on diffusion tensor measures of the brain. The purpose of this study was to evaluate the effect of head size or total intracranial volume on diffusion tensor measures (FA and MD). A total of 821 normal subjects (304 females and 517 males) were included...
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