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Despite high morbidity and mortality associated with lung diseases, addressing drugs towards lung tissue remains a pending task. Particle lung filtration has been proposed for passive lung targeting and drug delivery. However, toxicity issues derived from the long‐term presence of the particles must be overcome. By exploiting some of the ignored properties of nanosized metal–organic frameworks it...
Gummi‐Zauberkugeln: Neuartige, gegen Krebs wirkende Nanopartikel aus wohldefinierten amphiphilen Polymer‐Wirkstoff‐Konjugaten entstehen durch kontrolliertes Wachstum einer hydrophoben Polyisoprenkette ausgehend von einem Wirkstoff‐Makroinitiator unter Anwendung Nitroxid‐vermittelter Polymerisation (NMP; siehe Bild). Die Konjugate ordnen sich zu Nanopartikeln an, die eine hohe Wirkstoff‐Beladung sowie...
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