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Most chemotherapeutics are hydrophobic molecules and need to be converted into hydrophilic form before administration. Based on the excellent hydrophilicity and programmability of DNA, now, a general strategy to construct a precise drug‐containing DNA framework for cancer treatment is reported. In this novel drug delivery system, carbonethyl bromide‐modified camptothecin (CPT) is employed to directly...
Von beidem das Beste: Ein neuartiges amphiphiles Homopolymer, das aus einem Monomer mit einer hydrophoben (rot) und einer hydrophilen Gruppe (grün) synthetisiert wurde, unterliegt in wässriger Lösung einem Selbstorganisationsprozess. Dadurch entstehen redoxempfindliche Micellen mit mehreren Kernen und einer Schale, die sich für den Wirkstofftransport in der Krebstherapie eignen könnten.
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