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Equine influenza virus is a highly contagious agent that is capable of causing explosive outbreaks of respiratory disease among susceptible horse populations. The virus infects the mucosal cells of the upper and lower respiratory tract, and induces respiratory disease characterized by a harsh dry cough and fever. Infection is generally self-limiting and the majority of horses recover uneventfully;...
Replicon particles derived from a vaccine strain of Venezuelan equine encephalitis (VEE) virus were used as vectors for expression in vivo of the major envelope proteins (G L and M) of equine arteritis virus (EAV), both individually and in heterodimer form (G L /M). The immunogenicity of the different replicons was evaluated in horses, as was their ability to protectively immunize...
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