Search results for: Erkang Wang

Items from 1 to 20 out of 375 results

article

Current Advances on the Single‐Atom Nanozyme and Its Bioapplications

Chao Peng, Ruoyu Pang, Jing Li, Erkang Wang

Advanced Materials > 36 > 10 > n/a - n/a

Nanozymes, a class of nanomaterials mimicking the function of enzymes, have aroused much attention as the candidate in diverse fields with the arbitrarily tunable features owing to the diversity of crystalline nanostructures, composition, and surface configurations. However, the uncertainty of their active sites and the lower intrinsic deficiencies of nanomaterial‐initiated catalysis compared with...

article

Rapid Synthesis of Trimetallic Nanozyme for Sustainable Cascaded Catalytic Therapy via Tumor Microenvironment Remodulation

Xiuna Jia, Jin Wang, Erkang Wang

Advanced Materials > 36 > 7 > n/a - n/a

Tumor microenvironment (TME)‐responsive nanozyme‐catalyzed cancer therapy shows great potential due to its specificity and efficiency. However, breaking the self‐adaption of tumors and improving the sustainable remodeling TME ability remains a major challenge for developing novel nanozymes. Here, a rapid method is developed first to synthesize unprecedented trimetalic nanozyme (AuMnCu, AMC) with a...

article

Recent Developments of Atomically Dispersed Metal Electrocatalysts for Oxygen Reduction Reaction^†

Ruoyu Pang, Hongyin Xia, Jing Li, Shaojun Guo, more

Chinese Journal of Chemistry > 41 > 5 > 581 - 598

Oxygen reduction reaction (ORR) is the pivotal portion in many electrochemical energy conversion and storage technologies. However, the complex mechanisms and sluggish kinetics of ORR have also become one of the key issues hindering the development and application of these technologies. Recently, single‐atom catalysts (SACs) with well‐defined atomic active centers and theoretical 100% atomic utilization...

article

LMCD1 facilitates the induction of pluripotency via cell proliferation, metabolism, and epithelial‐mesenchymal transition

Zhikai Ye, Ge Chen, Cuicui Hou, Zhenlong Jiang, more

Cell Biology International > 46 > 9 > 1409 - 1422

Somatic cell reprogramming was achieved by lentivirus mediated overexpression of four transcription factors called OSKM: OCT3/4, SOX2, KLF4, and c‐MYC but it was not very efficient. Here, we reported that the transcription factor, LMCD1 (LIM and cysteine rich domains 1) together with OSKM can induce reprogramming of human dermal fibroblasts into induced pluripotent stem cells (iPSCs) more efficiently...

article

Emerging Dual‐Atomic‐Site Catalysts for Efficient Energy Catalysis

Weiyu Zhang, Yuguang Chao, Wenshu Zhang, Jinhui Zhou, more

Advanced Materials > 33 > 36 > n/a - n/a

Atomically dispersed metal catalysts with well‐defined structures have been the research hotspot in heterogeneous catalysis because of their high atomic utilization efficiency, outstanding activity, and selectivity. Dual‐atomic‐site catalysts (DASCs), as an extension of single‐atom catalysts (SACs), have recently drawn surging attention. The DASCs possess higher metal loading, more sophisticated and...

article

Rational Construction of Ruthenium‐Cobalt Oxides Heterostructure in ZIFs‐Derived Double‐Shelled Hollow Polyhedrons for Efficient Hydrogen Evolution Reaction

Libing Fan, Tian Meng, Mengxia Yan, Dewen Wang, more

Small > 17 > 26 > n/a - n/a

Transition metal oxides (TMOs) and their heterostructure hybrids have emerged as promising candidates for hydrogen evolution reaction (HER) electrocatalysts based on the recent technological breakthroughs and significant advances. Herein, Ru‐Co oxides/Co₃O₄ double‐shelled hollow polyhedrons (RCO/Co₃O₄‐350 DSHPs) with Ru‐Co oxides as an outer shell and Co₃O₄ as an inner shell by pyrolysis of core‐shelled...

article

Regulating Catalytic Activity of DNA‐Templated Silver Nanoclusters Based on their Differential Interactions with DNA Structures and Stimuli‐Responsive Structural Transition

Yuchun Guo, Mengmeng Lv, Jiangtao Ren, Erkang Wang

Small > 17 > 3 > n/a - n/a

This work reports exquisite engineering of catalytic activity of DNA‐templated silver nanoclusters (DNA‐AgNCs) based on unique adsorption phenomena of DNAs on DNA‐AgNCs and reversible transition between double and triple‐stranded DNAs. Four DNA homopolymers exhibit different inhibition effects on the catalytic activity of DNA‐AgNCs, poly adenine (polyA) > poly guanine (polyG) > poly cytosine...

article

Functionalized Graphene@Gold Nanostar/Lipid for Pancreatic Cancer Gene and Photothermal Synergistic Therapy under Photoacoustic/Photothermal Imaging Dual‐Modal Guidance

Xiuna Jia, Weiguo Xu, Zhikai Ye, Yuling Wang, more

Small > 16 > 39 > n/a - n/a

Nanomaterial‐based pancreatic cancer treatment has received widespread attention and rapid development in the past few years. The major challenges include the poor combination of diagnosis and therapy, the difficulty in targeting therapy from the root and the unsatisfactory antitumor efficiency, which is accompanied by a great risk of relapse and metastasis. In this work, a positively charged lipid...

article

Illuminating Diverse Concomitant DNA Logic Gates and Concatenated Circuits with Hairpin DNA‐Templated Silver Nanoclusters as Universal Dual‐Output Generators

Mengmeng Lv, Weijun Zhou, Daoqing Fan, Yuchun Guo, more

Advanced Materials > 32 > 17 > n/a - n/a

Exquisite administration of a new type of hairpin DNA‐templated silver nanoclusters (H‐AgNCs) as universal dual‐output generators in DNA‐based logic systems is reported. Diverse concomitant contrary logic gates (CCLGs) with opposite functions (YES^{^}NOT, OR^{^}NOR, INHIBIT^{^}IMPLICATION, XOR^{^}XNOR, and MAJORITY^{^}MINORITY) and extended concatenated logic circuits are presented and some of them perform specific...

article

A General Method for Transition Metal Single Atoms Anchored on Honeycomb‐Like Nitrogen‐Doped Carbon Nanosheets

Xiaoyan Zhang, Shan Zhang, Yong Yang, Liguang Wang, more

Advanced Materials > 32 > 10 > n/a - n/a

Excavating and developing highly efficient and cost‐effective nonnoble metal single‐atom catalysts for electrocatalytic reactions is of paramount significance but still in its infancy. Herein, reported is a general NaCl template‐assisted strategy for rationally designing and preparing a series of isolated transition metal single atoms (Fe/Co/Ni) anchored on honeycomb‐like nitrogen‐doped carbon matrix...

article

An ent‐Kaurane Diterpenoid Isolated from Rabdosia excisa Suppresses Bcr‐Abl Protein Expression in Vitro and in Vivo and Induces Apoptosis of CML Cells

Yan Xia, Miao Feng, Erkang Wang, Li Chen, more

Chemistry & Biodiversity > 16 > 10 > n/a - n/a

Chronic myelogenous leukemia (CML) is a disease of the blood stem cells that features the oncoprotein Bcr‐Abl. Tyrosine kinase inhibitors (TKIs) are used to treat CML patients, but these have limited efficacy due to the emergence of resistance via genetic mutation. Kamebakaurin is an ent‐kaurane diterpenoid that has been isolated from Rabdosia excisa (Maxim.) H.Hara. Herein, we investigate the potential...

article

Ni@RuM (M=Ni or Co) core@shell nanocrystals with high mass activity for overall water-splitting catalysis

Shan Zhang, Fan Lv, Xiaoyan Zhang, Yelong Zhang, more

Science China Materials > 2019 > 62 > 12 > 1868-1876

Developing efficient water-splitting electro-catalysts with high mass activity is in urgent need for large-scale sustainable production of hydrogen but, still remains as a big challenge. Herein, we report a one-pot method to fabricate a series of core@shell Ni@RuM (M=Ni or Co) nanocrystals (NCs) with Ni as the core and tunable RuM (M=Ni or Co) as the alloy shell for efficient water-splitting catalysis...

article

The emergence of the two cell fates and their associated switching for a negative auto-regulating gene

Zhenlong Jiang, Li Tian, Xiaona Fang, Kun Zhang, more

BMC Biology > 2019 > 17 > 1 > 1-14

Background Decisions in the cell that lead to its ultimate fate are important for fundamental cellular functions such as proliferation, growth, differentiation, development, and death. These cell fate decisions can be influenced by both the gene regulatory network and also environmental factors and can be modeled using simple gene feedback circuits. Negative auto-regulation is a common feedback motif...

article

A Molybdenum Carbide Nanotubes Modified Electrode as the Functionalized Sensing Platform for Electrochemical Detection of Dopamine

Ke Li, Yanchao Han, Jing Li, Huanhuan Xing, more

Electroanalysis > 31 > 5 > 922 - 926

In this work, molybdenum carbide (Mo₂C) nanotubes were prepared via the self‐degradable template method and high‐temperature calcination, and then were successfully used to modify glassy carbon electrode (CGE) for the high‐sensitivity determination of dopamine (DA) without the inference of ascorbic acid(AA) and uric acid (UA). The surface morphology of Mo₂C nanotubes has been investigated by scanning...

article

The Effect of Metal Components in the Quaternary Electrocatalysts on the Morphology and Catalytic Performance of Transition Metal Phosphides

Qiao Cao, Wenling Gu, Jing Li, Erkang Wang

Electroanalysis > 30 > 11 > 2584 - 2588

Development of low‐cost, earth‐abundant alternative electrocatalysts to platinum catalyst for hydrogen evolution reaction (HER) is of great significance. Some multimetallic transition metal phosphides have been synthesized recently. However, the impacts of metal components on the morphology and performance of catalyst were less discussed. In this communication, taking the quaternary phosphides Co_x...

article

Gold-silver bimetallic nanoclusters with enhanced fluorescence for highly selective and sensitive detection of glutathione

Qingfeng Zhai, Huanhuan Xing, Daoqing Fan, Xiaowei Zhang, more

Sensors and Actuators B: Chemical > 2018 > 273 > C > 1827-1832

Herein, a sensitive and selective “off-on” fluorescence sensor for the detection of glutathione (GSH) was fabricated based on Au-Ag bimetallic nanoclusters (NCs) with the assistance of persulfate (S₂O₈²⁻). The as-prepared Au-Ag bimetallic NCs with enhanced fluorescent intensity about 2.7-folds higher than pure Au NCs was performed due to the synergistic effect of two atoms, which can be quenched by...

article

Co₃O₄/Fe_0.33Co_0.66P Interface Nanowire for Enhancing Water Oxidation Catalysis at High Current Density

Xiaoyan Zhang, Jing Li, Yong Yang, Shan Zhang, more

Advanced Materials > 30 > 45 > n/a - n/a

Designing well‐defined nanointerfaces is of prime importance to enhance the activity of nanoelectrocatalysts for different catalytic reactions. However, studies on non‐noble‐metal‐interface electrocatalysts with extremely high activity and superior stability at high current density still remains a great challenge. Herein, a class of Co₃O₄/Fe_0.33Co_0.66P interface nanowires is rationally designed for...

article

Enhancement of the hydrogen evolution performance by finely tuning the morphology of Co-based catalyst without changing chemical composition

Wenling Gu, Liuyong Hu, Changshuai Shang, Jing Li, more

Nano Research > 2019 > 12 > 1 > 191-196

Transition-metal phosphides, as the promising alternatives to noble metal catalysts, have been widely used as efficient electrocatalysts for hydrogen evolution reaction (HER). In this work, three kinds of cobalt-8-hydroxyquinoline (Coq_x) with different size and nanostructures are synthesized by varying the hydrothermal conditions, which was named as Coq_x-L, Coq_x-M and Coq_x-S according to the decreased...

article

Integration of two-dimensional morphology and porous surfaces to boost methanol electrooxidation performances of PtAg alloy nanomaterials

Changshuai Shang, Yaxiao Guo, Erkang Wang

Nano Research > 2018 > 11 > 12 > 6375-6383

As an attempt to minimize the usage amounts of noble metals in catalysis, PtAg alloy nanocrystals with a porous nanosheet morphology were fabricated through a galvanic replacement reaction. During the reaction, ascorbic acid was added to the solution to protect the Ag triangular nanoplates from being totally etched. Structural characterizations indicated that the obtained nanocrystals had thin porous...

article

Nanozyme: An emerging alternative to natural enzyme for biosensing and immunoassay

Qingqing Wang, Hui Wei, Zhiquan Zhang, Erkang Wang, more

TrAC Trends in Analytical Chemistry > 2018 > 105 > C > 218-224

Nanozyme, a term defined for nanomaterial with enzyme-like properties, has attracted significant research attention owing to its striking merits. Recently, a surge of nanozymes have been demonstrated to catalyze some typical enzymatic reactions mimicking oxidase, peroxidase and catalase. Especially, nanozymes with peroxidase-like activity have grown into a big family due to their broad range of applications...

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INFONA - science communication portal

Search results for: Erkang Wang

Current Advances on the Single‐Atom Nanozyme and Its Bioapplications

Rapid Synthesis of Trimetallic Nanozyme for Sustainable Cascaded Catalytic Therapy via Tumor Microenvironment Remodulation

Recent Developments of Atomically Dispersed Metal Electrocatalysts for Oxygen Reduction Reaction^†

LMCD1 facilitates the induction of pluripotency via cell proliferation, metabolism, and epithelial‐mesenchymal transition

Emerging Dual‐Atomic‐Site Catalysts for Efficient Energy Catalysis

Rational Construction of Ruthenium‐Cobalt Oxides Heterostructure in ZIFs‐Derived Double‐Shelled Hollow Polyhedrons for Efficient Hydrogen Evolution Reaction

Regulating Catalytic Activity of DNA‐Templated Silver Nanoclusters Based on their Differential Interactions with DNA Structures and Stimuli‐Responsive Structural Transition

Functionalized Graphene@Gold Nanostar/Lipid for Pancreatic Cancer Gene and Photothermal Synergistic Therapy under Photoacoustic/Photothermal Imaging Dual‐Modal Guidance

Illuminating Diverse Concomitant DNA Logic Gates and Concatenated Circuits with Hairpin DNA‐Templated Silver Nanoclusters as Universal Dual‐Output Generators

A General Method for Transition Metal Single Atoms Anchored on Honeycomb‐Like Nitrogen‐Doped Carbon Nanosheets

An ent‐Kaurane Diterpenoid Isolated from Rabdosia excisa Suppresses Bcr‐Abl Protein Expression in Vitro and in Vivo and Induces Apoptosis of CML Cells

Ni@RuM (M=Ni or Co) core@shell nanocrystals with high mass activity for overall water-splitting catalysis

The emergence of the two cell fates and their associated switching for a negative auto-regulating gene

A Molybdenum Carbide Nanotubes Modified Electrode as the Functionalized Sensing Platform for Electrochemical Detection of Dopamine

The Effect of Metal Components in the Quaternary Electrocatalysts on the Morphology and Catalytic Performance of Transition Metal Phosphides

Gold-silver bimetallic nanoclusters with enhanced fluorescence for highly selective and sensitive detection of glutathione

Co₃O₄/Fe_0.33Co_0.66P Interface Nanowire for Enhancing Water Oxidation Catalysis at High Current Density

Enhancement of the hydrogen evolution performance by finely tuning the morphology of Co-based catalyst without changing chemical composition

Integration of two-dimensional morphology and porous surfaces to boost methanol electrooxidation performances of PtAg alloy nanomaterials

Nanozyme: An emerging alternative to natural enzyme for biosensing and immunoassay

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