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Purpose We evaluated extracellular matrix remodeling in human fetal and cryptorchidic gubernacula. Methods Gubernacula were obtained from 40 normal human fetuses aged 15–29 weeks postconception (WPC) and from 39 children aged 1.3–10 years who had been submitted to orchiopexy. Total collagen and glycosaminoglycan (GAG) concentrations were assessed as μg hydroxyproline and μg hexuronic acid per mg...
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