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Some 2-[(methyleneamino)oxyl-N-(guanidino)ethaneimines (10a-g) were synthesized as analogs of guanabenz-type benzylideneaminoguanidine α 2 -agonists (9) in which the aryl portion (Ar) is substituted by the [(methyleneamino)oxy]methyl moiety (MAOMM). The α 2 -adrenergic activity of compounds 10a-g was evaluated by functional tests on guinea-pig ileum. The MAOM-derivatives10a-g exhibited...
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