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Background and Aims
Whether patients with cirrhosis have increased risk of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection and the extent to which infection and cirrhosis increase the risk of adverse patient outcomes remain unclear.
Approach and Results
We identified 88,747 patients tested for SARS‐CoV‐2 between March 1, 2020, and May 14, 2020, in the Veterans Affairs (VA)...
Background and Aims
The augmenter of liver regeneration (ALR) protein is critical for lipid homeostasis and mitochondrial function. We investigated high‐fat/high‐carbohydrate (HF/HC) diet–induced nonalcoholic fatty liver disease (NAFLD) in wild‐type (WT), hepatocyte‐specific ALR‐knockout (ALR‐H‐KO), and ALR‐heterozygous (ALR‐H‐HET) mice. ALR was measured in serum of human nonalcoholic steatohepatitis...
Breakthroughs in hepatitis C virus (HCV) treatment and rising rates of intravenous drug use have led to an increase in the number of organ donors who are HCV antibody–positive but serum nucleic acid test (NAT)–negative. The risk of HCV transmission from the liver grafts of these donors to recipients is unknown. To estimate the incidence of HCV transmission, we prospectively followed 26 consecutive...
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