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In HIV/HCV co-infected patients, HIV-1 gp120 activates human hepatic stellate cells (HSCs) which play a key role in fibrosis pathogenesis. It is still unclear whether pro-fibrogenic effects are more attributable to X4 or R5 strains in vivo.To assess if HIV-1 X4 or R5 variants are associated with a different progression of fibrosis.A total of 105 HIV/HCV co-infected patients were submitted to gp120...
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