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For the 2011 FDA approved Parkinson’s Disease (PD) SPECT imaging agent I-123 labeled DaTscan, the volume of interest (VOI) is the interior portion of the brain. However imaging of the occipital lobe is also required with PD for calculation of the striatal binding ratio (SBR), a parameter of significance in early diagnosis, differentiation of PD from other disorders with similar clinical presentations,...
In hybrid brain imaging, the integration of CT for the purpose of providing attenuation correction has proven to provide substantial benefit to emission image quality. Unfortunately due to the sequential nature of the acquisitions this benefit may be reduced or even nullified if the patient fails to remain motion-less after the transmission image is acquired. In particular, the misalignment of the...
In this paper, using Defrise Phantoms, we present our investigations of the axial limitations of an analytical cone-beam reconstruction algorithm (FDK), and the iterative ordered-subset transmission reconstruction (OSTR) iterative algorithm, for an axially extended version of the Philips Brightview XCT cone beam CT (CBCT) geometry. Simulations were preformed for head size and body size Defrise Phantoms...
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