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Pediatric risk factors for postoperative morbidity after central node dissection are ill-defined.This outcome study aimed to evaluate operative morbidity in patients aged ≤18 years after total thyroidectomy with or without central node dissection for suspected or proven thyroid cancer.Included were 102 patients with hereditary C-cell hyperplasia, 66 patients with medullary, 60 patients with papillary,...
The appropriate resection for thyroid cancer invading the aerodigestive tract remains controversial.A total of 174 patients underwent resections for aerodigestive tract invasion from differentiated thyroid cancer (103 patients), medullary thyroid cancer (40 patients), and undifferentiated thyroid cancers/unusual thyroid neoplasms (31 patients). In all, 82 patients submitted to transmural resections...
Surgical strategy in patients with thyroid cancer (TC) infiltrating the aerodigestive system is controversial. This study was undertaken to examine the long-term results of cervical evisceration (CE).Since 1995, 14 consecutive patients with advanced TC underwent total laryngectomy (LE, n = 6) or esophagolaryngectomy (ELR, n = 8). Patients with unusual thyroid neoplasms or metastases to the thyroid...
Background. In patients with multiple endocrine neoplasia type 2A syndrome, prophylactic thyroidectomy is generally recommended at the age of 5 to 6 years. Whether this recommendation is justified for exon 13 mutations is unknown. Methods. We analyzed the clinical data from 40 patients harboring RET codon 790/791 mutations (exon 13) who had been treated in 4 specialized centers. Results. Mean age...
Background. Few lipid/atherosclerosis intervention trials have assessed the impact of cholesterol reduction on peripheral arterial disease. The 838 patients evaluated in the Program on the Surgical Control of the Hyperlipidemias (POSCH) trial represent more than the total number of patients in the seven previously reported studies.Methods. Peripheral arterial disease in POSCH was assesed by progression...
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