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Normal aging is commonly associated with decreased cognitive functions, which could be conspicuously alleviated by enriched environment (EE) with physical, social, and sensory stimuli, suggesting that aging brain still has intriguing plasticity. Multiple researches have been carried out to explore the structural and the molecular changes in aging brain, which would be considered for evidences that...
The age‐related changes, of the oligodendrocytes in rat subcortical white matter, were investigated in this study. The oligodendrocytes in subcortical white matter were labeled with anti‐2′,3′‐cyclic nucleotide 3′‐phosphodiesterase antibody (anti‐CNPase antibody, a specific marker of oligodendrocytes). The total number of CNPase+ cells was estimated with an unbiased stereological technique, the optical...
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