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Pituitary adenylate cyclase‐activating polypeptide (PACAP) receptor 1 (PAC1‐R) is the neuropeptide PACAP‐preferring receptor‐mediating neuroprotective activity. In order to clarify the biological mechanism of its expression, we cloned the 2,526 bp promoter fragment from −2,500 to +26 of the transcription initiation site of human ADCYAP1R1 gene and constructed the novel promotor reporter system named...