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Sommario Gli obiettivi della terapia della sindrome di Cushing sono la normalizzazione dei livelli di cortisolo, la riduzione dei segni e dei sintomi legati all’ipercorticismo e la rimozione della neoplasia responsabile dell’eccesso di ACTH o cortisolo. La terapia medica è oggi sempre più usata, soprattutto nei casi di persistenza di malattia dopo la chirurgia, o in attesa degli effetti della radioterapia...
Background and aim
Patients with adrenal insufficiency (AI) require lifelong glucocorticoid (GC) replacement therapy. Cortisol measurement in saliva is increasingly being used: we assessed salivary cortisol rhythm in outpatients with AI, to provide new insights regarding the management of GC treatment.
Materials and methods
Nineteen AI outpatients collected six saliva samples from awakening (Fa...
OBJECTIVE Measurement of Cortisol levels in saliva is a marker of free hormone. How salivary Cortisol rhythm is affected by age, gender, the metabolic syndrome and estrogen-progestin therapy was evaluated in a community sample of adults. SUBJECTS AND METHODS One hundred twenty volunteers recruited from the Hospital staff and family members of the Endocrinology Unit were instructed to collect 7 salivary...
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