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In this paper a computational model of gene level signaling for STP (Short Term Potentiation) and LTP (Long Term Potentiation) have been proposed. STP and LTP are prime signaling cascade for establishment of Episodic Memory in human brain. In various previous works receptor level signaling cascades are presented for STP and LTP. In this work signaling cascade at gene level through gene-gene interaction...
Accurate computational prediction of protein functions increasingly relies on network-inspired models for the protein function transfer. This task can become challenging for proteins isolated in their own network or those with poor or uncharacterized neighborhoods. Here, we present a novel probabilistic chain-graph-based approach for predicting protein functions that builds on connecting networks...
This paper addresses the protein classification problem, andexplores how its accuracy can be improved by using information fromtime-course gene expression data. The methods are tested on datafrom the most deadly species of the parasite responsible for malariainfections, Plasmodium falciparum. Even though avaccination for Malaria infections has been under intense study formany years, more than half...
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