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BackgroundCardiac gene transfer may serve as a novel therapeutic approach for heart disease. Numerous serotypes of recombinant adeno‐associated virus (rAAV) have been identified with variable tropisms to cardiac tissue.
MethodsBoth in vitro and in vivo experiments were undertaken to compare cardiac tropisms of rAAV‐2, 5, 7, 8 and 9. For the in vitro studies, 107 vector genome (vg) of rAAV‐2, 5, 7,...
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