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Our previous study found that the artery interposed to vein did not develop atherosclerosis but rather underwent atrophic remodeling in hyperlipidemic rabbits, suggesting that local hemodynamic load was another important determinant for the development of atherosclerosis. This study focused on the cellular and molecular changes in autologous artery grafts derived from rabbits fed with high lipid diet...
Autologous vein grafts interposed to arteries are susceptible to the development of accelerated atherosclerosis. The effect of grafted artery interposed to vein on the atherosclerosis development and vascular remodeling is unknown. We investigated, therefore, the morphologic changes of artery grafts to vein in hyperlipidemic rabbits. Left common carotid artery grafts, approximately 5cm long, were...
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