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Cultured murine bone marrow derived mast cells (BMMC) were found to store high levels of dopamine (3753+/-844 pg/10 7 cells) and occasionally produce norepinephrine and epinephrine. The catecholamine synthesis inhibitor, α-methyl-para-tyrosine, decreased intracellular catecholamine concentrations, and activation with ionomycin stimulated dopamine release. Neither dopaminergic receptor antagonists...
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