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Acute rejection (AR) remains a concern for kidney transplantation. Cytokines are key mediators in the induction and effector phases of all immune and inflammatory responses. Single nucleotide polymorphisms (SNPs) in cytokines and their receptors may relate to AR. We investigated the relation between AR and SNPs in the genes encoding for IL‐2(–330G>T), IL‐10(−592C>A and −1082G>A), TGF‐β1(915G>C),...
After clinical heart transplantation, ischemia, acute rejection, and repair mechanisms can trigger the up-regulation of cytokines. To investigate the cytokine profile early after transplantation, we monitored messenger RNA (mRNA) expression levels of tumor necrosis factor- (TNF-), monocyte chemoattractant protein-1 (MCP-1), transforming growth factor- (TGF-), platelet-derived growth factor-A (PDGF-A),...
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