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Background and Purpose
We recently identified donecopride as a pleiotropic compound able to inhibit AChE and to activate 5‐HT4 receptors. Here, we have assessed the potential therapeutic effects of donecopride in treating Alzheimer's disease (AD).
Experimental Approach
We used two in vivo animal models of AD, transgenic 5XFAD mice and mice exposed to soluble amyloid‐β peptides and, in vitro, primary...
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