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Observational studies cannot demonstrate causality. To demonstrate cause and effect requires an intervention study in which consumption of a nutrient, food or diet is altered in a controlled way and the effect on selected outcomes is measured. The study design process should include careful consideration of the hypothesis, duration, intervention, amount and mode of delivery, control and blinding,...
This study evaluated four food-derived peptides with known antihypertensive activities for antimicrobial activity against pathogenic microorganisms, and assessed structure–function relationships using alanine analogues. The peptides (EVSLNSGYY, barley; PGTAVFK, soybean; TTMPLW, α-casein; VHLPP, α-zein) and the six alanine substitution peptides of PGTAVFK were synthesised, characterised and evaluated...
Nutrition labelling is an important strategic approach for encouraging consumers to make healthier food choices. The availability of highly palatable foods labelled as ‘low fat or reduced calorie’ may encourage the over-consumption of these products. This study aimed to determine whether the manipulation of nutrition labelling information can influence food portion size consumption. Normal and overweight...
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