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A series of phenanthroindolizidine and phenanthroquinolizidine alkaloids and their 14-amino-derivatives (1–44) were prepared and systematically evaluated for their anti-tumor activities against A549 and HL60 cell lines. The bioassay results showed that most of these alkaloids possess good anti-tumor activities. Especially, compounds 15, 22, 28, 33–36, 40 and 42 displayed low nanomolar or subnanomolar...
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