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In this study, assisted by affinity-guided DMAP strategy, we developed a novel 19 F-modified lectin as a biosensor for specific detection and imaging of glycoproteins. Exploited the large chemical shift anisotropy property of 19 F nuclei, glycoproteins detected by our 19 F-biosensor are signatured by broadened peaks in 19 F NMR, hence enabled the distinction between...
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