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Mammea coumarins are isoprenylated 4-alkyl or 4-phenylcoumarins. Their distribution is limited to 3 Clusiaceae/Calophyllaceae genera. We recently reported on their presence in Mammea neurophylla bark extracts, where they exhibited anti-AGE properties associated with a prevention of the endothelial dysfunction. About 120 mammea coumarins were already described so, in order to focus further phytochemical...
Advanced glycation end-products (AGEs) are associated with many pathogenic disorders such as pathogenesis of diabetes or endothelial dysfunction leading to cardiovascular events. Therefore, the identification of new anti-AGE molecules or extracts aims at preventing such pathologies. Many Clusiaceae and Calophyllaceae species are used in traditional medicines to treat arterial hypertension as well...
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