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This paper presents discussion of quartz crystal microbalance (QCM) immunosensors for environmental monitoring. Factors limiting the practical application of antibodies to analytical problems are also presented. Among several candidates for the QCM immunosensor device, selected QCM devices and oscillating circuits were tested thoroughly and developed to obtain highly stable and sensitive frequency...
We focused immobilization method of anti-C-reactive protein (CRP) monoclonal antibody on a quartz crystal microbalance (QCM) when 2-aminoethanethiol, 4,4'-dithiodibutyric acid, and 11-mercaptoundecanoic acid were respectively deposited on the gold surface of QCM. In all monolayers, anti-CRP antibody was immobilized such as Langmuir types because it had been introduced with a corresponding active group...
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