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A drug nanocarrier based on silicon nanoparticles (SiNPs) is introduced for optical imaging‐guided cancer therapy by S.‐T. Lee, Y. He, and co‐workers on page 1029. The silicon nanocarriers featuring strong and stable fluorescence are superbly suitable for long‐term tumor cell tracking and cancer therapy, as well as promising for multi‐mode cancer treatment in vitro and in vivo. The picture shows how...
Silicon nanoparticle (SiNP) nanocarriers feature strong fluorescence, ultrasmall size, robust photostability, and tunable drug‐loading capacity. Using SiNP nanocarriers, the first example of long‐term cancer cell tracking is successfully demonstrated. Furthermore, in vivo experiments show that tumor‐bearing mice treated with SiNP nanocarriers survive over 20 d without observable tumor growth, demonstrating...
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