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Extracellular EDTA suppressed in a dose-dependent manner the phagocytosis of yeast particles byDictyostelium discoideum cells. Activity was restored fully by the addition of Ca 2+ , and partially by the addition of Mn 2+ or Zn 2+ , but Mg 2+ was ineffective. The pH-sensitive, Ca 2+ -specific chelator EGTA also inhibited phagocytosis at pH 7.5, but not at pH...
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