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High-molecular-weight mucin 2 (MUC2) glycoproteins show an aberrant glycosylation pattern when expressed in human colon carcinoma: the oligosaccharide chains are shorter and some are missing. In our ongoing effort of MUC2 vaccine development, we have solved the NMR structure of the all l-amino acid and various d-amino acid-substituted derivatives of the peptide TPTPTGTQTPT, previously identified as...
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