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In this study, we reported the preparation and evaluation of 177Lu-DOTA-RGD2, 177Lu-DOTA-Bz-RGD2 and 177Lu-DTPA-Bz-RGD2 (RGD2 = E[c(RGDfK)]2) as a potential therapeutic radiotracers for the treatment of integrin αvβ3-positive tumors. The BALB/c nude mice bearing the U87MG human glioma xenografts were used to evaluate the biodistribution characteristics and excretion kinetics of 177Lu-DOTA-RGD2, 177...
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