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Background Autoantigen La/SSB is molecular target of humoral autoimmunity in patients with primary Sjogren’s Syndrome (pSS) and systemic lupus erythematosus (SLE). In this study, we investigated the existence and possible influence of anti-idiotypic response to anti-La/SSB antibodies. Materials and Methods Synthetic peptide analogs (pep) of the major antigenic determinants of La/SSB (289–308aa and...
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