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A nonlabeling electrochemical detection method for analyzing the polymerase-chain-reaction-amplified sequence-specific p16INK4A gene, in which the basis for the covalent immobilization of deoxyribonucleic acid (DNA) probe is described, has been developed. The self-assembly process was based on the covalent coupling of glutaraldehyde (GA) as an arm molecule onto an amino-functional surface. The...
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