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Significance analysis of proteomic data generated by LC‐MS/MS is challenging owing to great data variability originated from biological, operational, and instrumental variations. Protein quantification by LC‐MS/MS either in absolute or relative scale is often highly skewed, which put limitations on model‐based statistical inference. For this purpose, we have developed an alternative nonparametric...
At the 12th Annual HUPO World Congress of Proteomics in Japan, the Human Proteome Project (HPP) presented 16 scientific workshop sessions. Here we summarize highlights of ten workshops from the Biology and Disease‐driven HPP (B/D‐HPP) teams and three from the HPP Resource Pillars. Highlights of the three Chromosome‐centric HPP sessions appeared in the many articles of the 2014 C‐HPP special issue...
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