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A phosphine-containing ligand providing a N-{N-[3-(diphenylphosphino)propionyl]glycyl}-L-S-benzyl-cystein (PNNS) donor atomset for the chelation of 99m Tc was studied in labelling experiments with a model peptide (tetragastrin, cholecystokinin-fragment). The peptide was conjugated to the ligand chelator by active ester chemistry either before or after radiolabelling. Both the chelator-conjugate...
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