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It has been previously documented that the main features and sensing performance of electrograms (EGMs) recorded in implantable cardioverter defibrillators (ICDs) depend on lead configuration. Although this dependence has been ascribed to differences in lead sensitivity and spatial resolution, the quantification of these two properties on ICD has not yet been attempted. In this paper, an operative...
Current Sequential Cardiac Navigation Systems (SCNS) are widely used for creating either voltage or delay maps of the heart, allowing the physician to determine adequate therapy strategies and ablation targets. Given that the number or recorded electrograms (EGM) is a major determinant of the clinical procedure duration, our aim was to propose a method suitable for analyzing the spatial sampling rate...
Vasovagal Syncope (VVS) represents the most frequent cause of loss of consciousness. Additionally to its clinical usefulness, the tilt test is a good quality physiological gold standard for the spectral analysis of Heart Rate Variability (HRV). Noise removal in HRV signals is problematic, due to the presence of ectopic beats and non-stationary short-term trends. Given current Tilt Test systems simultaneously...
Lead design is a critical factor for detecting and redetecting lethal arrhythmias in electrograms (EGM) from Implantable Cardioverter Defibrillators (ICD). The estimation of the scope of a lead can help to elucidate the anatomical origin of recorded EGM and explain signal features. In this paper, we compare quantitatively the scope of true and integrated bipolar sensing leads by combining bioelectric...
The long QT syndrome type-3 (LQT3) is an inherited cardiac disorder caused by mutations in the sodium channel gene SCN5A. LQT3 has been associated with ventricular arrhythmias and sudden cardiac death, specially at low heart rates. Based on computer simulations and experimental investigations, analysis of the morphology of the action potential (AP) has shown that it undergoes early after depolarizations...
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