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Les traitements thrombolytiques ont été employés dans le traitement des oblitérations artérielles depuis 40 ans par voie systémique et depuis 1971 par voie locale. Plusieurs études randomisées, publiées dans les années 1990 comparant le traitement thrombolytique au traitement chirurgical de référence ont montré l'intérêt du traitement thrombolytique, en mesurant, néanmoins, les risques et les complications...
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