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At the first day of lactation, maternal rats were injected with a single i.p. dose of 100 or 250 mg/kg body weight of a mixture of polychlorinated biphenyls (Aroclor 1254). This treatment caused significant increases in both material and neonatal hepatic cytochrome P-450, cytochrome b 5 , and cytochrome-c-(P-450) reductase. Transfer of PCBs via lactation resulted in significant increases...
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