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Objectives The aim of the present study was to measure the effects of a 5,000-ppm F toothpaste on caries-related factors in dental plaque and saliva. Materials and methods A 6-week clinical trial was designed with a total of 34 participants, of which 26 completed the study. The participants were assessed on four visits, 2 weeks apart. Sampling of approximal fluid for fluoride analysis and approximal...
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