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Always on the move: Solution NMR spectroscopy revealed a high degree of intrinsic mobility for the homotrimeric viral coat protein gp41: a prehairpin intermediate (left) may sample a range of relative orientations of the C‐terminal and N‐terminal heptad repeats, possibly in exchange with a low population of the late‐fusion six‐helical bundle (right; FP: fusion peptide, TM: transmembrane helix).
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