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To gather preliminary data examining whether dehydration and/or exposure to monosodium glutamate (MSG) may influence pain in Meru, Kenya.Two small pilot studies were conducted in Meru, Kenya after community report of high chronic pain in the region. First, a prevalence estimate was conducted among 89 participants from random households. Second, widespread chronic pain participants, recruited from...
In contrast to women with relatively asymptomatic endometriosis, women with endometriosis-associated chronic pelvic pain (CPP) exhibit nonpelvic hyperalgesia and decreased gray matter volume in key neural pain processing regions. Although these findings suggest central pain amplification in endometriosis-associated CPP, the underlying changes in brain chemistry and function associated with central...
Proton magnetic resonance spectroscopy has been used extensively in the study of various neurobiological disorders: depression, schizophrenia, autism, etc. But its application to chronic pain is relatively new. Not many studies in chronic pain have used 1 H-MRS. The unique ability of 1 H-MRS to assess both static and dynamic levels of glutamate and γ-aminobutyric acid (GABA) gives...
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