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Premenopausal women are at a lower risk of coronary heart diseases relative to age matched men. However, the underlying mechanisms are not clearly understood. This article studies the effects of 17β-estradiol (17β-E 2 ) at physiological concentrations on the cholesterylester metabolism in macrophages (J774 A.1 cells) with a particular focus on neutral cholesterol esterase (N-CEase). Cells...
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