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Human erythrocyte membranes catalyse the NAD(P)H-dependent generation of the semiquinone of an adriamycin-type antibiotic carminomycin under anaerobic conditions. The maximal yield of the antibiotic radical is about 4-fold higher in the presence of NADPH than of NADH. The possible significance of the antibiotic reduction to the semiquinone by a human erythrocyte membrane redox chain for the clinical...
Omówiono syntezę i zastosowanie różnych rodzajów znakowanych spinowo
związków biologicznie czynnych. Poszczególne klasy tych związków obejmują:
sulfonamidy, antybiotyki, witaminy, związki znieczulające i estry choliny,
alkaloidy i leki przeciwnowotworowe.
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