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In the present study, susceptibility weighted imaging (SWI) was used to show atrophy of cerebellar nuclei in spinocerebellar ataxia type 6 (SCA6), Friedreich ataxia (FRDA), and spinocerebellar ataxia type 3 (SCA3). We tested the hypothesis that cerebellar nuclei are smaller in FRDA and SCA3 compared to healthy controls, but relatively preserved in SCA6. In addition, 7T fMRI was performed with optimized...
This study established the relationship between kinematic and grip force parameters in prehension tasks, disease severity and cerebellar atrophy in patients with cerebellar degeneration.Prehension was tested in a condition during which the hand reached out, grasped, and lifted an object. Task complexity was modified by limiting the transport component to a single-joint movement, and introducing a...
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