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Piezodynamic Cancer Therapy
In article number 2300437, Tae Il Lee, Min Suk Shim, and co‐workers develop piezocatalytic 2D WS2 nanosheets incorporated with mitochondria‐targeting moieties and glycolysis inhibitors. The piezoelectric 2D WS2 nanosheets efficiently generate reactive oxygen species by piezoelectric polarization under ultrasound irradiation. The WS2 nanosheets enable the selective and effective...
Piezoelectric nanomaterials that can generate reactive oxygen species (ROS) by piezoelectric polarization under an external mechanical force have emerged as an effective platform for cancer therapy. In this study, piezoelectric 2D WS2 nanosheets are functionalized with mitochondria‐targeting triphenylphosphonium (TPP) for ultrasound (US)‐triggered, mitochondria‐targeted piezodynamic cancer therapy...
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